Monday, 14 November 2011 04:24

Headaches in Children

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Abstract

This article summarizes idiopathic headaches in childhood, differentiating the clinical characteristics from those of intracranial hypertension. There is a discussion on migraine treatment, the importance of environmental influences and the less well recognized risk posed by analgesic overuse leading to chronic refractory headaches.

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Abstract

Sexually acquired oncogenic Human Papillomavirus (HPV) types are important co-factors in the development of anogenital tract malignancies. HPV vaccines are a major primary prevention strategy against cervical cancer, other HPV-associated malignancies, cervical dysplasia and genital warts. Improving vaccination uptake is key to the future success of the HPV vaccination programme, and could potentially be achieved by involving GPs, sexual health services and providers in its delivery.

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Abstract

Type 2 diabetes is increasingly prevalent, and is associated with increased morbidity and mortality. Studies have shown the benefit of tight glycaemic control in reducing complications, but with many conventional treatments this can result in weight gain and hypoglycaemia. Newer treatments may lessen these problems, but evidence of their long term efficacy is lacking.

Wednesday, 29 February 2012 11:44

Editorial

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The planned NHS reforms have kept our medical leaders and politicians very busy over the last few months. The focus has been on the process of commissioning and who should have control of the financial levers, the problem of the private sector cherry picking the lucrative elements and conflict of interest of GPs. The previous structure of PCTs was mired in stagnation, planning blight with an emphasis on managing the finances and not the delivery of care. Any reform that allows us to put clinicians at the front end of the decision making process will be better than what we have had in the past, even if there are warts on the new framework. The public still trust doctors more than most other professional groups, including politicians!

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Abstract

Temporal arteritis (TA) also known as giant cell arteritis (GCA) is the most commonly occurring chronic vasculitis, typically affecting individuals older than 50 years. GCA typically manifests as new onset headache with features of systemic illness although presentation is highly variable. Because many conditions can mimic GCA, accurate diagnosis is essential to avoid over-treatment.

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Abstract

Polycystic Ovarian Syndrome (PCOS) is a common disorder with clinical manifestations of anovulatory infertility and hyperandrogenism with oligomenorrhea/amenorrhoea, hirsuitism and acne. There is a higher prevalence of obesity, impaired glucose tolerance, type2 diabetes, hyperinsulinaemia and adverse cardiovascular profile in these patients. The complicated interplay between genetic factors, abdominal obesity and insulin resistance play a key role in pathophysiology. Management should be tailored to individual needs. The understanding of the principles of management of long term implications aids to offer holistic approach to this disorder. Many different therapies may be offered to regulate menstrual cycle, induce ovulation and improve signs of hyperandrogenism. Lifestyle improvement and weight reduction are the most important predictors of long term health.

Wednesday, 29 February 2012 11:20

Clinical Focus Prmiary care:Skin Cancer

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ABSTRACT:

Skin cancer is the most common cancer in the United Kingdom and incidence rates are increasing. This article explains the common presentation, clinical features, referral guidelines, management and prognosis of both non-melanoma skin cancer (basal cell carcinoma and squamous cell carcinoma) and melanoma.

Wednesday, 29 February 2012 11:24

Insulin Management in Type 2 Diabetes

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Abstract

This article discusses key issues which underpin the theoretical and practical aspects of initiation and maintenance of insulin therapy in patients with Type 2 Diabetes (T2D). It is a complex area with many different insulin preparations, injection devices and regimens. The intention is to provide guidance to help Primary Care teams better understand some of the issues around insulin management in T2D.

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