Lipids and especially raised low-density lipoprotein cholesterol (LDL-C) are a key contributor to cardiovascular disease risk. Genetic dyslipidaemias including familial hypercholesterolaemia are common. Statins, ezetimibe and proprotein convertase subtilisin kexin-9 (PCSK9) inhibitors treatment are effective. The role of triglyceride drugs such as fibrates and omega-3 fatty acids is less clear.
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